The QuickBooks error 15215 appears if you have installed Improper or impartial QuickBooks setup or have a malware or virus in your system, or corrupted payroll file (s) in the system, the error may appear. Additionally, the error also occurs if there is a corrupted window in Quickbooks or you have deleted a QuickBooks file or files intentionally or mistakenly. However, running background applications at the time of software update is the root cause of this error.